Application
Western blot analysis of KCNC3 expression in Y79 whole cell lysate.| Product Name | KCNC3 Antibody (N-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | KCNC3 (Potassium voltage-gated channel subfamily C member 3) is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. The corneal epithelium is an important cell layer that functions to separate the corneal stroma from the anterior chamber of the eye. Increased expression of KCNC3 in confluent corneal endothelial cells suggests that the ionic current maintained by KCNC3 acts to regulate the hydration and transparency of the corneal stroma. Potassium channel regulation is also important for the high-frequency firing of cerebellar neurons. Defects, primarily missense mutations, in the gene encoding the KCNC3 protein have been attributed to neurological developmental disorders and adult onset neurological diseases. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHC |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of KCNC3 of mouse rat and human origin by WB IP IF and IHC(P) |
|---|---|
| Tissue Specificity | recommended for detection of KCNC3 of mouse, rat and human origin by WB, IP, IF and IHC(P) |
| Entrez Gene | 3748 |
|---|
Application
Western blot analysis of KCNC3 expression in Y79 whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
