Application
Western blot analysis of BIRC8 expression in MOLT-4 whole cell lysate.| Product Name | BIRC8 Antibody (C-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. BIRC8 (baculoviral IAP repeat-containing 8), also known as ILP2, is a 236 amino acid protein that localizes to the cytoplasm and contains one BIR repeat and one RING-type zinc finger motif. Expressed in normal testis, as well as in cancerous tissue, BIRC8 functions to protect cells against Bax-mediated apoptosis, suggesting a possibly role in tumor transformation and progression. The gene encoding BIRC8 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, several ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIP |
| recommended for detection of BIRC8 of human origin by WB and IP | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of BIRC8 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of BIRC8 of human origin |
| Entrez Gene | 112401 |
|---|
Application
Western blot analysis of BIRC8 expression in MOLT-4 whole cell lysate.| Application Notes | recommended for detection of BIRC8 of human origin by WB and IP |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
