| Product Name | UGRP1 Antibody (M-139) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Uteroglobin-related protein 1 (UGRP1) is a 93-amino acid secretory protein that is mainly expressed in lung Clara-like epithelial cells, with low levels of expression in the thyroid. The homodimeric UGRP1 may play an anti-inflammatory role in lung inflammation, though the mechanism is still unknown. A macrophage scavenger receptor with collagenous structure (MARCO) acts as a receptor for UGRP1 and may be involved in pathogen clearance in the lung. UGRP1 has a binding site for bacterial lipopolysaccharide (LPS). It is downregulated in antigen-induced inflamed airways, such as allergic asthma, but is upregulated in cystic fibrosis, and interleukin-9 and interleukin-5 modulate UGRP1 expression. UGRP1 may be a therapeutic candidate for treating various sources of lung inflammation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of UGRP1 of mouse and, to a lesser extent, rat and human origin by WB, IP, IF and ELISA may cross-react with UGRP2 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-139 representing full length UGRP1 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-139 representing full length UGRP1 of mouse origin |
| Entrez Gene | 117158 |
|---|
| Application Notes | recommended for detection of UGRP1 of mouse and, to a lesser extent, rat and human origin by WB, IP, IF and ELISA may cross-react with UGRP2 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Data sheet for OM204196