Application
Western blot analysis of PEG3 expression in A204 whole cell lysate.| Product Name | PEG3 Antibody (X-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Paternally-expressed gene 3 protein (PEG3), also known as PW1 or ZSCAN24, is a 1588 amino acid protein that localizes to the nucleus and cytoplasm. The PEG3 gene, which is thought to encode a transcription factor, is an imprinted gene that is expressed from the paternal allele in embryos. A member of the Krüppel C2H2-type zinc-finger protein family, PEG3 is highly expressed in brain, astrocytes, glial cells, uterus, embroyo, placenta, ovary and testis. In neurons with DNA damage, PEG3, in cooperation with SIAH-1, interacts with p53, c-Myc and Bax to induce apoptosis. Also, PEG3 associates specifically with TRAF2 to activate NF˚B p50 and thus inhibit TNF-induced apoptosis. Three isoforms of PEG3 are expressed due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of PEG3 of human origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against PEG3 of human origin |
|---|---|
| Tissue Specificity | raised against PEG3 of human origin |
| Entrez Gene | 5178 |
|---|
Application
Western blot analysis of PEG3 expression in A204 whole cell lysate.| Application Notes | recommended for detection of PEG3 of human origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
