Application
Western blot analysis of BTBD10 expression in human fetal muscle tissue extract.| Product Name | KBTBD10 Antibody (D-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | KBTBD10 (Kelch repeat and BTB domain-containing protein 10), also known as Kel-like protein 23, sarcosin or Kelch-related protein 1, is a 606 amino acid cytoplasmic protein found in sarcomeric muscle. KBTBD10 plays an important role in the protein ubiquitination pathway by acting as the substrate-specific adaptor of an E3 ubiquitin-protein ligase complex. KBTBD10 forms this complex with CUL-3 and Rbx1, and also interacts with N-RAP. Although predominantly cytoplasmic, KBTBD10 can co-localize with Actin at the ruffle-like membrane structures located at the tips of pseudopodia, indicating a role in pseudopod elongation in transformed cells. KBTBD10 contains five Kelch repeats and one BTB (POZ) domain. Due to alternative splicing events, KBTBD10 exists as two isoforms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of KBTBD10 of mouse, rat, human and canine origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against KBTBD10 of human origin |
|---|---|
| Tissue Specificity | raised against KBTBD10 of human origin |
| Entrez Gene | 10324 |
|---|
Application
Western blot analysis of BTBD10 expression in human fetal muscle tissue extract.| Application Notes | recommended for detection of KBTBD10 of mouse, rat, human and canine origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
