Application
Western blot analysis of CHIC1 expression in Jurkat whole cell lysate.| Product Name | CHIC1 Antibody (Y-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | In mammals, X-chromosome inactivation is required to ensure equivalent levels of gene expression from the sex chromosomes. X chromosome inactivation in mammals requires the X inactivation center (XIC) and the Xist (X inactive specific transcript) gene product, which is exclusively expressed from the inactive chromosome. CHIC1 (cysteine-rich hydrophobic domain 1), also known as BRX (brain X-linked protein), is a 224 amino acid protein that is encoded by a gene which localizes to the XIC candidate region of the X chromosome. Localizing to the cell membrane and to cytoplasmic vesicles, CHIC1 is palmitoylated and preferentially expressed in brain. In mice, CHIC1 is normally X-inactivated. Due to the chromosomal location of the CHIC1 gene, it is believed that CHIC1 may play a role in certain X-linked mental retardation syndromes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of CHIC1 of mouse, rat, human, canine and zebrafish origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against CHIC1 of human origin |
|---|---|
| Tissue Specificity | raised against CHIC1 of human origin |
| Entrez Gene | 53344 |
|---|
Application
Western blot analysis of CHIC1 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of CHIC1 of mouse, rat, human, canine and zebrafish origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
