Application
Western blot analysis of CA VII expression in non-transfected: (A) and human CA VII transfected: (B) 293T whole cell lysates.Application
Western blot analysis of CA VII expression in non-transfected: (A) and human CA VII transfected: (B) 293T whole cell lysates.| Product Name | CA VII Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA VII, also known as carbonate dehydratase VII, is a highly conserved mammlian carbonic anhydrase. It localizes to the cytoplasm and is ubiquitiously expressed at low levels, but is present at significant levels in brain and salivary glands. CA VII may influence GABAergic excitation in neurons and contribute to the triggering of convulsions common to neurological disorders. Due to the high expression level of CA VII in brain, it may be useful in the development of pharmacologic agents for managing epilepsy and Alzheimer’s disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CA VII of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-90 mapping at the N-terminus of CA VII of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-90 mapping at the N-terminus of CA VII of human origin |
| Entrez Gene | 766 |
|---|
Application
Western blot analysis of CA VII expression in non-transfected: (A) and human CA VII transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of CA VII expression in non-transfected: (A) and human CA VII transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of CA VII of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
