Application
Western blot analysis of p41-ARCb expression in non-transfected 293T: (A), mouse p41-ARCb transfected 293T: (B), HeLa (C), PC-3 (D), SK-BR-3 (E) and COLO 320DM (F) whole cell lysates.Application
Western blot analysis of p41-ARCb expression in human platelet whole cell lysate.Application
Western blot analysis of p41-ARCb expression in non-transfected: (A) and mouse p41-ARCb transfected: (B) 293T whole cell lysates.| Product Name | p41-ARCb Antibody (H-54) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The Arp2/3 (Actin-related protein 2/3) complex consists of seven subunits, all of which are actin-related proteins. The complex is involved in the control of actin polymerization and in mediating the formation of branched actin networks. The p41 subunit of Arp2/3 exists in multiple versions which arise due to post-translational modifications and vary in function depending on cell type or developmental stage. p41-ARCb, also known as ARPC1B (Actin-related protein 2/3 complex subunit 1B) or ARC41 (Arp2/3 complex 41 kDa subunit), is a 372 amino acid version of the p41 subunit of the Arp2/3 complex. Localized to the cytoplasm and cytoskeleton, p41-ARCb is involved in regulating the assembly and maintenance of the complex and, unlike the other Arp2/3 subunits, is not primarily involved in actin polymerization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of p41-ARCb of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 291-344 mapping near the C-terminus of p41-ARCb of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 291-344 mapping near the C-terminus of p41-ARCb of human origin |
| Entrez Gene | 10095 |
|---|
Application
Western blot analysis of p41-ARCb expression in non-transfected 293T: (A), mouse p41-ARCb transfected 293T: (B), HeLa (C), PC-3 (D), SK-BR-3 (E) and COLO 320DM (F) whole cell lysates.
Application
Western blot analysis of p41-ARCb expression in human platelet whole cell lysate.
Application
Western blot analysis of p41-ARCb expression in non-transfected: (A) and mouse p41-ARCb transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of p41-ARCb of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
