The Arp2/3 (Actin-related protein 2/3) complex consists of seven subunits, all of which are actin-related proteins. The complex is involved in the control of actin polymerization and in mediating the formation of branched actin networks. p20-ARC, also known as ARPC4 (Actin-related protein 2/3 complex subunit 4) or ARC20 (Arp2/3 complex 20 kDa subunit), is a 168 amino acid actin-binding component of Arp2/3. Localized to the cytoplasm and cytoskeleton, p20-ARC can, unlike other actin-related proteins, interact with several of the Arp2/3 subunits. This suggests that p20-ARC acts as a hub in the complex and may play a key role in Arp2/3 complex formation. Two isoforms of p20-ARC exist due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of p20-ARC of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-168 representing full length p20-ARC of human origin
Tissue Specificity
epitope corresponding to amino acids 1-168 representing full length p20-ARC of human origin
Western blot analysis of p20-ARC expression in 293T (A) and HeLa (B) whole cell lysates.
Application Notes
recommended for detection of p20-ARC of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.