| Product Name | SID-1 Antibody (M-95) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | SID-1 and SID-2 belong to the systemic RNA interference defective-1 (SID1) family of transmembrane proteins. SID-1, originally identified in C. elegans, is an 827 amino acid protein. It localizes to the cell membrane and contains eleven transmembrane domains. This suggests that SID-1 possibly functions as a channel protein. The overexpression of SID-1 enhances double stranded RNA (dsRNA) uptake in pancreatic ductal adenocarcinoma cells. SID-2, also first identified in C. elegans, is an 832 amino acid protein with multiple transmembrane domains. At least two isoforms exist for SID-2 due to alternative splicing. Isoform 2 contains an additional 21 amino acids after residue 387 and has an alternate sequence that is 8 amino acids shorter for residues 814 to 832 of isoform 1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SID-1 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA non cross-reactive with isoform 2 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-95 mapping within an N-terminal extracellular domain of SID-1 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-95 mapping within an N-terminal extracellular domain of SID-1 of mouse origin |
| Entrez Gene | 54847 |
|---|
| Application Notes | recommended for detection of SID-1 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA non cross-reactive with isoform 2 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
