Application
Western blot analysis of OSR1 expression in SW480 nuclear extract.Application
Western blot analysis of OSR1 expression in non-transfected: (A) and mouse OSR1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of OSR1 expression in non-transfected: (A) and human OSR1 transfected: (B) 293T whole cell lysates.| Product Name | TMP21 Antibody (H-38) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | OSR (odd-skipped related) proteins belong to the Odd C2H2-type zinc-finger protein family and are involved in embryonic development and bone formation. OSR1 (odd-skipped-related 1), also designated ODD, is a 266 amino acid protein that is expressed in the colon, small intestine, prostate, testis and fetal lung. OSR1 is upregulated in several pancreatic and esopha-geal cancer cell lines and downregulated in some primary gastric cancers. OSR1 contains three C2H2-type zinc fingers, a tyrosine phosphorylation site, and several putative PXXP SH3 binding motifs. OSR1 may play a critical role in metanephric kidney formation. Absence of OSR1 in mice causes lack of formation of the meta-nephric mesenchyme and null expression of EYA1, Six2, Pax, Sall1 and GDNF, which are proteins involved in normal kidney development. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of OSR1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 129-166 mapping within an internal region of OSR1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 129-166 mapping within an internal region of OSR1 of human origin |
| Entrez Gene | 130497 |
|---|
Application
Western blot analysis of OSR1 expression in SW480 nuclear extract.
Application
Western blot analysis of OSR1 expression in non-transfected: (A) and mouse OSR1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of OSR1 expression in non-transfected: (A) and human OSR1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of OSR1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
