| Product Name | Tim17B Antibody (M-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Tim17B, also known as Timm17b (mitochondrial import inner membrane translocase subunit Tim17B), is a 172 amino acid multi-pass membrane protein that belongs to the Tim17/Tim22/Tim23 family. Tim17B is an essential component of the Tim23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. The complex is composed of at least Tim23, Tim17 (Tim17A or Tim17B) and Tim50, and it interacts with the Tim44 component of the PAM complex. Tim17B expression is abundant in heart and skeletal muscle, intermediate in brain, and weak in pancreas, placenta, kidney and liver. The gene that encodes Tim17B maps to human chromosome Xp11.23. Human chromosome X consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently, as males carry a single X chromosome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of Tim17B of mouse and rat origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of Tim17B of mouse origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of Tim17B of mouse origin |
| Entrez Gene | 1 |
|---|
| Application Notes | recommended for detection of Tim17B of mouse and rat origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
