Application
Western blot analysis of MFSD7 expression in non-transfected 293T: (A), human MFSD7 transfected 293T: (B), MCF7 (C) and HeLa (D) whole cell lysates.| Product Name | MFSD7 Antibody (S-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The major facilitator superfamily consists of presumed carbohydrate transporters with ten to twelve membrane-spanning domains. MFSD7 (major facilitator superfamily domain-containing protein 7), also known as LP2561, is a 560 amino acid multi-pass membrane protein that belongs to the major facilitator superfamily. Existing as three alternatively spliced isoforms, MFSD7 is likely a carrier that transports small solutes by using chemiosmotic ion gradients. Significantly, a related protein, MFSD2, may play a role in placenta morphogenesis and may also be involved in adaptive thermogenesis. The gene encoding MFSD7 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MFSD7 isoforms 1-4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other MFSD family members | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of MFSD7 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of MFSD7 of human origin |
| Entrez Gene | 84179 |
|---|
Application
Western blot analysis of MFSD7 expression in non-transfected 293T: (A), human MFSD7 transfected 293T: (B), MCF7 (C) and HeLa (D) whole cell lysates.| Application Notes | recommended for detection of MFSD7 isoforms 1-4 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other MFSD family members |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
