Application
Western blot analysis of LIGHT expression in mouse spleen tissue extract.Application
Western blot analysis of LIGHT expression in rat spleen tissue extract.Application
Immunofluorescence staining of normal mouse liver frozen section showing cytoplasmic and extracellular staining.| Product Name | LIGHT Antibody (FL-240) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Herpes virus entry mediator (HVEM), a type I transmembrane protein, is a member of the TNF receptor superfamily. HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD). HVEM also binds two cellular ligands, secreted lymphotoxin a and light. LIGHT is a member of the TNF superfamily produced by activated T cells. This type II transmembrane protein competes with HSV glycoprotein D for binding to HVEM. LIGHT is closely related in sequence to lymphotoxin ∫ (LT∫) and can also bind to the LT∫ receptor. LIGHT is also known to induce apoptosis and suppress tumor formation.The gene encoding LIGHT maps to human chromosome 19p13.3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LIGHT of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-240 representing full length LIGHT of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-240 representing full length LIGHT of human origin |
| Entrez Gene | 8740 |
|---|
Application
Western blot analysis of LIGHT expression in mouse spleen tissue extract.
Application
Western blot analysis of LIGHT expression in rat spleen tissue extract.
Application
Immunofluorescence staining of normal mouse liver frozen section showing cytoplasmic and extracellular staining.| Application Notes | recommended for detection of LIGHT of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
