Application
Western blot analysis of Peroxin 6 expression in non-transfected: (A) and human Peroxin 6 transfected: (B) 293T whole cell lysates.| Product Name | Peroxin 6 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including ∫-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. One such member of the Peroxin gene family is Peroxin 6. Of 11 mutations identified in the gene Pex6, most led to premature termination or large deletions of the Peroxin 6 protein and resulted in the most severe peroxisome biogenesis disorder phenotype of Zellweger syndrome, a disorder associated with major deformations. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Peroxin 6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Peroxin 6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Peroxin 6 of human origin |
| Entrez Gene | 5190 |
|---|
Application
Western blot analysis of Peroxin 6 expression in non-transfected: (A) and human Peroxin 6 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Peroxin 6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
