Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic and nuclear staining of glandular cells.Application
Western blot analysis of human recombinant LOXL1 fusion protein.Application
Western blot analysis of LOXL1 expression in Jurkat whole cell lysate.| Product Name | LOXL1 Antibody (H-165) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Lysyl oxidase (LOX) proteins belong to a family of enzymes that oxidize primary amine substrated to reactive aldehydes. In fibrillar collagens and elastin, LOX catalyzes the lysine-derived cross-links of collagen fibrils and insoluble elastic fibers in the extracellular matrix. It can localize both to the nucleus and the cytoplasm. LOX is involved in tumor suppression, cell motility, cellular senescence and developmental regulation. There are four homologs of LOX, lysyl oxidase-like proteins, designated LOX-like (LOXL1-LOXL4) proteins. LOXL1 is an extracellular protein that localizes specifically to sites of elastogenesis. It serves as a cross-linking enzyme, controlling the deposition of elastin. LOXL1 interacts with Fibulin-5. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LOXL1 of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 96-260 mapping within an internal region of LOXL1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 96-260 mapping within an internal region of LOXL1 of human origin |
| Entrez Gene | 4016 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human small intestine tissue showing cytoplasmic and nuclear staining of glandular cells.
Application
Western blot analysis of human recombinant LOXL1 fusion protein.
Application
Western blot analysis of LOXL1 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of LOXL1 of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
