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Glycophorin A Antibody (H-60)

Catalog Number:OM204775
OM204775
Discount Price
OM204775-100ul
1~2 Week
100ul
OM204775-50ul
50ul
OM204775-20ul
20ul
1~2 Week
Product Profile
Product Name Glycophorin A Antibody (H-60)
Antibody Type Primary Antibodies
Modification Notes Glycophorins A, B and C are sialoglycoproteins of the human erythrocyte membrane, which bear the antigenic determinants for the MN, Ss and Gerbich blood groups, respectively. Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. The human Glycophorin A gene maps to chromosome 4q31.21, contains 7 exons which are 97% homologous to Glycophorin B, and encodes a 150 amino acid protein. The human Glycophorin B gene maps to chromosome 4q31.21 and encodes a 91 amino acid protein. The human Glycophorin C gene maps to chromosome 2q14.3 and contains four exons. Glycophorin C transcript can generate two protein isoforms. Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein. Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, which specifies the Yus subtype of the Gerbich phenotype.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIPIFIHCELISA
recommended for detection of Glycophorin A of human origin by WB, IP, IF, IHC(P) and ELISA
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Alternative Names epitope corresponding to amino acids 46-105 of Glycophorin A of human origin
Tissue Specificity epitope corresponding to amino acids 46-105 of Glycophorin A of human origin
Database Links
Entrez Gene 2993
Application

Application

Immunoperoxidase staining of formalin fixed, paraffin-embedded human urothelial cancer showing membrane staining of tumor cells (low and high magni?fication). Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Application

Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing membrane localization.

Application

Western blot analysis of human recombinant Glycophorin A fusion protein.
Application Notes recommended for detection of Glycophorin A of human origin by WB, IP, IF, IHC(P) and ELISA
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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