Application
Western blot analysis of TIMP-1 expression in non-transfected: (A) and human TIMP-1 transfected: (B) 293T whole cell lysates and human recombinant TIMP-1 (C).Application
Western blot analysis of human recombinant TIMP-1 fusion protein.| Product Name | TIMP-1 Antibody (H-150) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (tissue inhibitor of metalloproteinases 1, 2, 3 and 4) complex with metalloproteinases such as collagenases, gelatin-ases and stromelysins, resulting in irreversible inactivation of the metallopro-teinase. TIMP-1 has been found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus and remodeling of the extracellular matrix during the folding of epithelia and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart, with low levels expressed in liver, brain, lung, thymus and spleen. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TIMP-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 58-207 mapping at the C-terminus of TIMP-1 (tissue inhibitor of metalloproteinase-1) of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 58-207 mapping at the C-terminus of TIMP-1 (tissue inhibitor of metalloproteinase-1) of human origin |
| Entrez Gene | 7076 |
|---|
Application
Western blot analysis of TIMP-1 expression in non-transfected: (A) and human TIMP-1 transfected: (B) 293T whole cell lysates and human recombinant TIMP-1 (C).
Application
Western blot analysis of human recombinant TIMP-1 fusion protein.| Application Notes | recommended for detection of TIMP-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
