Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islets of Langerhans and glandular cells.Application
Western blot analysis of cathepsin B expression in 293T whole cell lysate.Application
Western blot analysis of cathepsin B expression in LS1034 (A) and WI 38 (B) whole cell lysate.| Product Name | cathepsin B Antibody (FL-339) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of cathepsin B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-339 representing full length cathepsin B of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-339 representing full length cathepsin B of human origin |
| Entrez Gene | 1508 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islets of Langerhans and glandular cells.
Application
Western blot analysis of cathepsin B expression in 293T whole cell lysate.
Application
Western blot analysis of cathepsin B expression in LS1034 (A) and WI 38 (B) whole cell lysate.| Application Notes | recommended for detection of cathepsin B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
