Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of Kinectin 1 expression in rat testis tissue extract.Application
Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.| Product Name | Kinectin 1 Antibody (H-190) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The kinesin family of motor proteins comprise at least two forms of conventional kinesin, which are encoded by different genes and designated as ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells (1,2). The motor protein kinesin is a heterotetramer composed of two heavy chains and two light chains (3,4). While the kinesin heavy chain contains the motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding (5). Kinesin-driven vesicle motility is dependent upon kinectin 1, a kinesin-binding protein (6). Kinectin 1, also known as kinesin receptor, is an integral membrane protein in the ER (7–9). Despite the kinesin-kinectin 1 interaction, a great deal of debate surrounds the involvement of kinectin 1 in microtubule-dependent transport (2,10). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of Kinectin 1 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine and canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1156-1345 mapping near the C-terminus of Kinectin 1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1156-1345 mapping near the C-terminus of Kinectin 1 of human origin |
| Entrez Gene | 3895 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human fallopian tube tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of Kinectin 1 expression in rat testis tissue extract.
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.| Application Notes | recommended for detection of Kinectin 1 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine and canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
