Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing cytoplasmic and nuclear staining of respiratory epithelial cells.Application
Western blot analysis of Trio expression in WI 38 whole cell lysate.| Product Name | Trio Antibody (H-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1731-1850 mapping within an internal region of Trio of human origin |
| Modification Notes | Protein tyrosine phosphatases, or PTPs, are type I transmembrane proteins, membrane-associated proteins or proteins localized in nuclei. Examples of transmembrane PTPs are LAR, PTPa, PTPb, PTPg, PTPd, PTPe, PTPz, PTPk and PTPm. Transmembrane PTPs play diverse roles during development and in adult tissues. Immunodepletion studies have suggested LAR to be a regulator of insulin receptor phosphorylation. Trio is a LAR-interacting protein that contains two functional guanine nuclear exchange factor (GEF) domains and a serine/threonine protein kinase (PSK) domain. One of the the Trio-GEF domains exhibits Rac-specific GEF activity while the other exibits Rho-specific GEF activity. The carboxy terminal PSK domain is most similar to the PSK domains of the CaMK family. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of Trio of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1731-1850 mapping within an internal region of Trio of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1731-1850 mapping within an internal region of Trio of human origin |
| Entrez Gene | 7204 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing cytoplasmic and nuclear staining of respiratory epithelial cells.
Application
Western blot analysis of Trio expression in WI 38 whole cell lysate.| Application Notes | recommended for detection of Trio of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
