Application
Western blot analysis of CD93 expression in non-transfected: (A) and human CD93 transfected: (B) 293T whole cell lysates.| Product Name | CD93 Antibody (H-190) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 463-652 mapping at the C-terminus of CD93 of human origin |
| Modification Notes | The CD93 antigen is a 652 amino acid cell-surface glycoprotein expressed by monocytes, neutrophils, platelets, microglia, and endothelial cells. CD93 was originally thought to be a putative receptor for the complement component C1q, a serum glycoprotein which plays an integral role in the activation of the classical pathway in response to immune complexes. As a result, in the literature the CD93 gene product has also been referred to as C1QR1 and C1qRp as well as MXRA4 (Matrix-remodeling-associated protein 4). Recent studies suggest that the CD93 antigen plays a role in intercellular adhesion and in clearance of apoptotic cells. CD93 is a heavily O-glycosylated, type I transmembrane protein consisting of an N-terminal domain with homology to C-type lectin domains, a tandem array of EGF-like domains, a single transmembrane domain and a short cytoplasmic tail. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CD93 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 463-652 mapping at the C-terminus of CD93 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 463-652 mapping at the C-terminus of CD93 of human origin |
| Entrez Gene | 22918 |
|---|
Application
Western blot analysis of CD93 expression in non-transfected: (A) and human CD93 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of CD93 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
