| Product Name | Integrin α8 Antibody (H-180) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 791-970 of Integrin α8 of human origin |
| Modification Notes | Integrins are heterodimers composed of noncovalently associated transmembrane å and ∫ subunits. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. Integrin å8 is expressed in contractile interstitial cells and smooth muscle cells and is upregulated in lung injury. Integrin å8 is also a marker for smooth muscle cells, expressed as early as alpha smooth muscle actin. The Integrin å8 chain is expressed in the glomerulus exclusively by mesangial cells and may play an important role for maintaining tissue integrity in the glomerulus during glomerular injury. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Integrin α8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 791-970 of Integrin &alpha 8 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 791-970 of Integrin α8 of human origin |
| Entrez Gene | 8516 |
|---|
| Application Notes | recommended for detection of Integrin α8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
