Application
Western blot analysis of Integrin α1 expression in PC-12 whole cell lysate.Application
Western blot analysis of rat recombinant Integrin α1 fusion protein.| Product Name | Integrin α1 Antibody (R-164) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 980-1143 mapping at the C-terminus of Integrin α1) also designated CD49α) of rat origin |
| Modification Notes | Integrins are heterodimers composed of noncovalently associated transmembrane å and ∫ subunits. The 16 å and 8 ∫ subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Integrin α1 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 980-1143 mapping at the C-terminus of Integrin &alpha 1) also designated CD49&alpha ) of rat origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 980-1143 mapping at the C-terminus of Integrin α1) also designated CD49α) of rat origin |
| Entrez Gene | 3672 |
|---|
Application
Western blot analysis of Integrin α1 expression in PC-12 whole cell lysate.
Application
Western blot analysis of rat recombinant Integrin α1 fusion protein.| Application Notes | recommended for detection of Integrin α1 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
