Application
Western blot analysis of RHBDL2 expression in PANC1 whole cell lysate.| Product Name | RHBDL2 Antibody (U-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of RHBDL2 of human origin by WB, IP and ELISA |
| Modification Notes | Members of the rhomboid family of integral membrane proteins are related to Drosophila Rhomboid-1, a serine protease that cleaves the membrane domain of the Drosophila EGF-family protein, Spitz, to release a soluble growth factor. RHBDL2 (rhomboid, veinlet-like 2), also known as rhomboid-related protein 2 or RRP2, is a 303 amino acid multi-pass membrane protein belonging to the rhomboid family. As an intramembrane serine protease, RHBDL2 cleaves type-1 transmembrane domains and releases soluble growth factors by cleaving membrane-bound substrates, specifically ephrin-B2 and ephrin-B3. Two isoforms of RHBDL2 exist as a result of alternative splicing events, and RHBDL2 is encoded by a gene mapping to human chromosome 1p34.3. Chromosome 1 spans about 260 million base pairs, makes up 8% of the human genome and contains approximately 3,000 genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of RHBDL2 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of RHBDL2 of human origin by WB, IP and ELISA |
| Entrez Gene | 54933 |
|---|
Application
Western blot analysis of RHBDL2 expression in PANC1 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
