Application
Western blot analysis of ACE2 expression in non-transfected: (A) and mouse ACE2 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of ACE2 expression in Hs 181.Tes whole cell lysate (A) and mouse kidney tissue extract (B).| Product Name | ACE2 Antibody (H-175) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 631-805 mapping at the C-terminus of ACE2 of human origin |
| Modification Notes | Angiotensin-converting enzyme (ACE) is a carboxyl-terminal dipeptidyl exopeptidase that converts angiotensin I to the potent vasopressive hormone, angiotensin II. There are two isoforms of ACE, the pulmonary ACEP and the testicular ACET. ACEP is a glycoprotein expressed in vascular endothelial cells of the lung, liver, adrenal cortex, pancreas, kidney and spleen. The ACET isoform is expressed exclusively in adult testis by developing sperm cells, specifically late pachytene spermatocytes. Additionally, ACE inactivates bradykinin, a vasodepressor peptide, and is involved in blood pressure regulation and fluid/electrolyte homeostasis. ACE2 is the first known human homolog of ACE. Unlike ACE, which is expressed ubiquitously throughout the vasculature, ACE2 is expressed only in cardiac, renal and testicular cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ACE2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 631-805 mapping at the C-terminus of ACE2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 631-805 mapping at the C-terminus of ACE2 of human origin |
| Entrez Gene | 59272 |
|---|
Application
Western blot analysis of ACE2 expression in non-transfected: (A) and mouse ACE2 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of ACE2 expression in Hs 181.Tes whole cell lysate (A) and mouse kidney tissue extract (B).| Application Notes | recommended for detection of ACE2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
