| Product Name | LT-β Antibody (FL-244) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-244 representing full length lymphotoxin-β (LT-β) of human origin |
| Modification Notes | Tumor necrosis factor (TNF) and lymphotoxin-a (LT-a, also known as TNFa) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. LT-b (lymphotaxin-b or TNFC) is a type II membrane protein with significant homology to TNF, LT-a and the ligand for the CD40 receptor. LT-a is present on the surface of activated T, B and LAK cells as a complex with LT-b. LT-b, also expressed by active lymphocytes, forms a heterotrimer with LT-a on the cell surface and anchors LT-a to the cell surface. A TNF receptor-related protein, the LT-b receptor (also known as TNFC receptor), is the human receptor for the LT-a/LT-b heterotri-mer. There are two LT-b isoforms expressed in human lymphoid cell lines and non-Hodgkin’s lymphomas. The gene which encodes LT-b maps to the major histocompatibility complex region on human chromosome 6p21.33. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LT-β of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-244 representing full length lymphotoxin-&beta (LT-&beta ) of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-244 representing full length lymphotoxin-β (LT-β) of human origin |
| Entrez Gene | 4050 |
|---|
| Application Notes | recommended for detection of LT-β of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
