epitope corresponding to amino acids 771-894 mapping at the C-terminus of Axl of human origin
Modification Notes
The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse (also designated Tyro3, Sky, Brt, Dtk, Etk2 and Tif), Axl (also designated UFO or ARK) and Mer (also designated Nyk or Eyk). Rse is expressed preferentially in the adult brain with lower expression in other tissues. Axl is found at highest levels in heart and skeletal muscle. Mer has been identified as a tyrosine kinase potentially involved in the development of glioblastomas. It is expressed at highest levels in ovary, prostate, lung and kidney. Gas6, a growth arrest specific gene, and the related anticoagulation factor Protein S, have been identified as ligands for the UFO family of receptors.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Axl of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 771-894 mapping at the C-terminus of Axl of human origin
Tissue Specificity
epitope corresponding to amino acids 771-894 mapping at the C-terminus of Axl of human origin
Western blot analysis of Axl expression in non-transfected: (A) and human Axl transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of Axl of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.