epitope corresponding to amino acids 121-173 mapping near the N-terminus of PCPE-1 of human origin
Modification Notes
Fibrillar collagen proteins are synthesized as procollagens that contain carboxyl- and amino-terminal peptide extensions (C- and N-propeptides). As procollagen is secreted from cells, these propeptides are cleaved and form mature helical fibrils. Procollagen C-endopeptidase enhancer 1 precursor (PCPE-1), also designated Type I procollagen COOH-terminal proteinase enhancer or PCOLCE, binds to the C-terminal propeptide of Type I procollagen. It is an extracellular matrix glycoprotein that can heighten the activity of procollagen C-proteinase in a substrate-specific way. PCPE-1 can greatly stimulate the action of tolloid metalloproteinases during procollagen processing. Expression of PCPE-1 has been shown to be highest in type I collagen-rich connective tissues such as skin and tendon.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of PCPE-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 121-173 mapping near the N-terminus of PCPE-1 of human origin
Tissue Specificity
epitope corresponding to amino acids 121-173 mapping near the N-terminus of PCPE-1 of human origin
recommended for detection of PCPE-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.