Application
Western blot analysis of ZNF271 expression in mouse skeletal muscle (A) and human skeletal muscle (B) tissue extracts.| Product Name | ZNF271 Antibody (N-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of ZNF271 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF271 (Zinc finger protein 271), also known as Zinc finger protein 7, HZF7 and Epstein-Barr virus-induced zinc finger protein, is a 655 amino acid nuclear protein that contains 19 C2H2-type zinc fingers. ZNF271 is expressed in pancreatic islet cells, T-cell lines, thryoid and thymocytes. Interestingly, ZNF271 plays a significant role in Epstein-Barr virus transformation. The gene encoding ZNF271 maps to a chromosomal region that is frequently associated with hematopoietic malignancies. There are two isoforms of ZNF271 that are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZNF271 of human and, to a lesser extent, mouse origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of ZNF271 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of ZNF271 of human origin |
| Entrez Gene | 10778 |
|---|
Application
Western blot analysis of ZNF271 expression in mouse skeletal muscle (A) and human skeletal muscle (B) tissue extracts.| Application Notes | recommended for detection of ZNF271 of human and, to a lesser extent, mouse origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
