| Product Name | PTPLAD2 Antibody (N-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of PTPLAD2 of human origin |
| Modification Notes | PTPLAD2 (protein tyrosine phosphatase-like A domain containing 2), also known as HACD4 (3-hydroxyacyl-CoA dehydratase 4), is a 232 amino acid multi-pass membrane protein that belongs to the very long-chain fatty acids dehydratase HACD family. Localizing to endoplasmic reticulum membrane, the PTPLAD2 protein is responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis. Highly expressed in leukocytes, and low expression in heart, spleen, kidney and placenta, the PTPLAD2 protein interact with the condensation enzymes of the ELOVL family. The PTPLAD2 gene is conserved in chimpanzee, dog, cow, mouse, rat and chicken, and maps to human chromosome 9p21.3. Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PTPLAD2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with HSPC121 also reactive with additional species, including bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of PTPLAD2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of PTPLAD2 of human origin |
| Entrez Gene | 401494 |
|---|
| Application Notes | recommended for detection of PTPLAD2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with HSPC121 also reactive with additional species, including bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
