| Product Name | SYNJ2BP Antibody (H-82) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 64-145 mapping at the C-terminus of SYNJ2BP of human origin |
| Modification Notes | SYNJ2BP (Synaptojanin-2-binding protein), also known as mitochondrial outer membrane protein 25 (OMP25) or ARIP2, is a 145 amino acid mitochondrial outer membrane protein that contains one PDZ (DHR) domain. The PDZ domain on SYNJ2BP binds to isoform 2A of Synaptojanin 2. The gene that encodes SYNJ2BP contains 50,595 bases and maps to human chromosome 14q24.2. Housing over 700 genes, chromosome 14 comprises nearly 3.5% of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer’s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder å1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SYNJ2BP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 64-145 mapping at the C-terminus of SYNJ2BP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 64-145 mapping at the C-terminus of SYNJ2BP of human origin |
| Entrez Gene | 55333 |
|---|
| Application Notes | recommended for detection of SYNJ2BP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
