| Product Name | PLSCR3 Antibody (H-72) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 90-161 mapping within an internal region of PLSCR3 of human origin |
| Modification Notes | The calcium-dependent mitochondrial membrane protein PLSCR3 (phospholipid scramblase 3), also known as PLS3, is a member of the phospholipid scramblase (PLS) family. The PLS family consists of membrane-bound enzymes that participate in the bi-directional movement of phospholipids. PLSCR3 is expressed in a wide variety of tissues but is not found in brain, liver or testis. It is involved in the regulation of mitochondrial respiratory function, morphology and apoptotic responses. More specifically, PLSCR3 is responsible for mediating the transport of cardiolipin from the inner mitochondrial membrane to the outer mitochondrial membrane. Cardiolipin is a major polyglycerophospholipid that plays a role in the regulation of mitochondrial enzymes involved in the generation of ATP. PLSCR3 activity is activated/phosphorylated by PKC ∂ and PLSCR3 functions as a downstream effector in PKC ∂-induced apoptosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PLSCR3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 90-161 mapping within an internal region of PLSCR3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 90-161 mapping within an internal region of PLSCR3 of human origin |
| Entrez Gene | 57048 |
|---|
| Application Notes | recommended for detection of PLSCR3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
