Application
Western blot analysis of 3632451O06Rik expression in non-transfected: (A) and mouse 3632451O06Rik transfected: (B) 293T whole cell lysates.| Product Name | C14orf37 Antibody (C-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within a C-terminal cytoplasmic domain of C14orf37 of human origin |
| Modification Notes | C14orf37 (chromosome 14 open reading frame 37) is a 774 amino acid protein single-pass type I membrane protein that exists as three alternatively spliced isoforms. The gene encoding C14orf37 maps to human chromosome 14q23.1. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder å1-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of 3632451O06Rik of mouse origin, C14orf37 of human origin and RGD1310110 of rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a C-terminal cytoplasmic domain of C14orf37 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within a C-terminal cytoplasmic domain of C14orf37 of human origin |
| Entrez Gene | 145407 |
|---|
Application
Western blot analysis of 3632451O06Rik expression in non-transfected: (A) and mouse 3632451O06Rik transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of 3632451O06Rik of mouse origin, C14orf37 of human origin and RGD1310110 of rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
