epitope mapping within an internal region of C2orf29 of human origin
Modification Notes
C2orf29 (chromosome 2 open reading frame 29), also known as C40, is a 510 amino acid protein that belongs to the UPF0760 family and is encoded by a gene that maps to human chromosome 2q11.2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of C2orf29 of human origin, D1Bwg0212e of mouse origin and RGD1560909 of rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of C2orf29 of human origin
Tissue Specificity
epitope mapping within an internal region of C2orf29 of human origin
Western blot analysis of C2orf29 expression in non-transfected: (A) and human C2orf29 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of C2orf29 of human origin, D1Bwg0212e of mouse origin and RGD1560909 of rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.