| Product Name | group V PLA2 Antibody (M-137) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-137 representing full length group V PLA2 of mouse origin |
| Modification Notes | Phospholipase A2s (PLA2s) constitute a family of esterases that hydrolyze the sn-2-acyl ester bond in glycerophospholipid molecules. These enzymes are generally calcium-dependent and have been found both intra- and extracellularly. By hydrolyzing the sn-2 bond in glycerophospholipids, PLA2s release fatty acids. One such fatty acid, arachidonic acid, generates the substrates for the initiation of the arachidonic acid cascade that produces various eicosanoids (i.e., prostaglandins, leukotrienes and thromboxanes), many of which are potent mediators of inflammation. PLA2s include both the relatively low molecular weight group I, group II and group V enzymes and the form known as cytoplasmic PLA2 (cPLA2). cPLA2 is present in macrophages, and hydrolyzes the sn-2 fatty acyl ester bond of phospholipids to produce a free fatty acid and a lysophospholid. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of group V PLA2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA may cross-react with other phospholipase A2 family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-137 representing full length group V PLA2 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-137 representing full length group V PLA2 of mouse origin |
| Entrez Gene | 5322 |
|---|
| Application Notes | recommended for detection of group V PLA2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA may cross-react with other phospholipase A2 family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
