Application
Western blot analysis of TM expression in non-transfected: (A) and mouse TM transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TM expression in non-transfected: (A) and human TM transfected: (B) 293T whole cell lysates.Application
Immunofluorescence staining of normal mouse intestine frozen section showing membrane staining.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human tonsil tissue showing membrane staining.| Product Name | TM Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 22-321 mapping within the extracellular domain of thrombomodulin (TM) of human origin |
| Modification Notes | Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCFCELISA |
| recommended for detection of thrombomodulin of mouse, rat and human origin by WB, IP, IF, IHC(P), FCM and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 22-321 mapping within the extracellular domain of thrombomodulin (TM) of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 22-321 mapping within the extracellular domain of thrombomodulin (TM) of human origin |
| Entrez Gene | 7056 |
|---|
Application
Western blot analysis of TM expression in non-transfected: (A) and mouse TM transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TM expression in non-transfected: (A) and human TM transfected: (B) 293T whole cell lysates.
Application
Immunofluorescence staining of normal mouse intestine frozen section showing membrane staining.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human tonsil tissue showing membrane staining.| Application Notes | recommended for detection of thrombomodulin of mouse, rat and human origin by WB, IP, IF, IHC(P), FCM and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
