Application
Western blot analysis of SPACR expression in non-transfected: (A) and human SPACR transfected: (B) 293T whole cell lysates.| Product Name | SPACR Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 121-420 mapping within an internal region of SPACR of human origin |
| Modification Notes | SPACR (sialoprotein associated with cones and rods), also known as IMPG1 (interphotoreceptor matrix proteoglycan 1) or IPM150 (interphotoreceptor matrix proteoglycan of 150 kDa), is a 797 amino acid secreted protein that contains two SEA domains. Possibly interacting with hyaluronan, SPACR may help to form a basic macromolecular scaffold comprising the insoluble interphotoreceptor matrix. SPACR is abundantly expressed in retina, where it is specifically expressed by cone and rod photoreceptor cells. The gene that encodes SPACR consists of approximately 151,564 bases and maps to human chromosome 6q14. With 170 million base pairs, chromosome 6 comprises nearly 6% of the human genome. Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SPACR of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 121-420 mapping within an internal region of SPACR of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 121-420 mapping within an internal region of SPACR of human origin |
| Entrez Gene | 3617 |
|---|
Application
Western blot analysis of SPACR expression in non-transfected: (A) and human SPACR transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of SPACR of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
