| Product Name | PPA1 Antibody (H-62) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 228-289 mapping at the C-terminus of PPA1 of human origin |
| Modification Notes | PPA1 (Pyrophosphate phospho-hydrolase 1), also known as IOPPP (inorganic pyrophosphatase), PP1, PP or PPase, belongs to the PPase family of inorganic pyrophosphatases. Inorganic pyrophosphatases catalyze the intracellular conversion of pyrophosphate to inorganic phosphate, a key reaction for phosphate metabolism in cells. PPA1 is a ubiquitously expressed protein that localizes to the cytoplasm and is required for cell growth. It exists as a homodimer exhibiting magnesium dependent activity. The binding of two magnesium ions is required to stimulate PPA1 activity; however, both subunits in the homodimer are capable of binding four magnesium ions. The additional ions are useful in forming complexes with substrates and products. In addition, the activity of PPA1 can be inhibited by calcium. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PPA1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 228-289 mapping at the C-terminus of PPA1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 228-289 mapping at the C-terminus of PPA1 of human origin |
| Entrez Gene | 5464 |
|---|
| Application Notes | recommended for detection of PPA1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
