| Product Name | YTHDF1 Antibody (A-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of YTHDF1 of human origin |
| Modification Notes | The YTH domain family protein family (YTHDF) includes YTHDF1, YTHDF2 and TYHDF3. YTHDF1, also designated Dermatomyositis associated with cancer putative autoantigen 1 (DACA-1), is a 559 amino acid protein that contains one YTH domain, which is a potential RNA binding domain. YTHDF2, also designated High-glucose-regulated protein 8, CLL-associated antigen KW-14 or Renal carcinoma antigen NY-REN-2, is a 579 amino acid protein that also contains one YTH domain. YTHDF3 is a 585 amino acid protein that also contains one YTH domain. The gene encoding YTHDF1 maps to chromosome 20, which houses over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of YTHDF1 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of YTHDF1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of YTHDF1 of human origin |
| Entrez Gene | 54915 |
|---|
| Application Notes | recommended for detection of YTHDF1 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
