TSSC4 (tumor suppressing subtransferable candidate 4), also known as tumor-suppressing STF cDNA 4 protein, is a 239 amino acid protein that exists as two alternatively spliced isoforms and belongs to the TSSC4 family. Widely expressed in nearly all adult tissues, TSSC4 is also found in fetal liver, lung, kidney and brain. The gene encoding TSSC4 maps to human chromosome 11p15.5, in a region that is thought to be associated with a tumor-suppressing region that, if altered, can lead to lung, ovarian and breast cancer, rhabdomyosarcoma, Beckwith-Wiedemann syndrome, Wilms’ tumor, low birth weight and adrenocortical carcinoma.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TSSC4 isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with TSSC1 or TSSC3
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of TSSC4 of human origin
Tissue Specificity
epitope mapping within an internal region of TSSC4 of human origin