Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine pancreas and islet cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of human recombinant IFN-β fusion protein.| Product Name | IFN-β Antibody (FL-187) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-187 representing full length IFN-β1 of human origin |
| Modification Notes | The genes encoding type I interferons (IFNs), which include 14 IFN-å genes, one IFN-∫ gene, one IFN-w (also known as IFN-å II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-å and -∫ are cytokines that are widely known to induce potent antiviral activity. IFN-å and -∫ exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-å, IFN-∫ or IFN-©, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-åR) interacts with IFN-å, IFN-∫ and IFN-w, and seems to be a multisubunit receptor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of IFN-β of human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-187 representing full length IFN-&beta 1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-187 representing full length IFN-β1 of human origin |
| Entrez Gene | 3456 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of exocrine pancreas and islet cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of human recombinant IFN-β fusion protein.| Application Notes | recommended for detection of IFN-β of human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
