Application
Western blot analysis of SLC12A8 expression in non-transfected: (A) and mouse SLC12A8 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of SLC12A8 expression in non-transfected: (A) and human SLC12A8 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of SLC12A8 expression in non-transfected: (A) and human SLC12A8 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of SLC12A8 expression in non-transfected: (A) and human SLC12A8 transfected: (B) 293T whole cell lysates.| Product Name | SLC12A8 Antibody (C-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of SLC12A8 of human origin |
| Modification Notes | SLC12A8 (solute carrier family 12 member 8) is a 714 amino acid multi-pass membrane protein that belongs to the SLC12A transporter family. The SLC12A8 protein is nearly ubiquitously expressed with very low level in normal skin, and highest levels in small intestine, stomach, testis, thyroid and colon. SLC12A8 is a cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation. The SLC12A8 protein shows homology to Na/K/Cl cotransporters, a family of membrane proteins responsible for electroneutral ion transport across a variety of cell types. It has been suggested that SLC12A8 could be identified as a candidate gene for psoriasis susceptibility. SLC12A8 is retinoid responsive. Existing as five alternatively spliced isoforms, the SLC12A8 gene is conserved in chimpanzee, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito and C.elegans, and maps to human chromosome 3q21.2. The SLC12A8 gene contains 13 exons and spans over 100 kb. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SLC12A8 of mouse and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of SLC12A8 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of SLC12A8 of human origin |
| Entrez Gene | 84561 |
|---|
Application
Western blot analysis of SLC12A8 expression in non-transfected: (A) and mouse SLC12A8 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of SLC12A8 expression in non-transfected: (A) and human SLC12A8 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of SLC12A8 expression in non-transfected: (A) and human SLC12A8 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of SLC12A8 expression in non-transfected: (A) and human SLC12A8 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of SLC12A8 of mouse and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
