Application
Western blot analysis of APCDD1L expression in Hep G2 (A), K-562 (B), Hs 67 (C), SH-SY5Y (D), MIA PaCa-2 (E) and Caki-1 (F) whole cell lysates.| Product Name | APCDD1L Antibody (G-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of APCDD1L of human origin |
| Modification Notes | APCDD1 (adenomatosis polyposis coli down-regulated 1), also known as B7323, DRAPC1 or FP7019, is a 514 amino acid single-pass type I membrane protein whose transcription is regulated by the ∫-catenin/ITF-2 complex. Expressed in high levels in ovary, heart, pancreas and prostate, with lower levels in spleen, lung, kidney, liver and colon, APCDD1 is thought to function as a developmental target of the ∫-catenin pathway and may play an important role in colorectal tumorigenesis. The gene encoding human APCDD1 maps to chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of APCDD1L of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of APCDD1L of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of APCDD1L of human origin |
| Entrez Gene | 164284 |
|---|
Application
Western blot analysis of APCDD1L expression in Hep G2 (A), K-562 (B), Hs 67 (C), SH-SY5Y (D), MIA PaCa-2 (E) and Caki-1 (F) whole cell lysates.| Application Notes | recommended for detection of APCDD1L of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
