| Product Name | GalNAc-TL1 Antibody (E-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of GalNAc-TL1 of human origin |
| Modification Notes | The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-TL1 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1), also known as GALNT16, is a 588 amino acid single-pass type II membrane protein belonging to the glycosyltransferase 2 family, which localizes to the Golgi apparatus. GalNAc-TL1 utilizes manganese and calcium as cofactors, and catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, which involves the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Containing one ricin B-type lectin domain, GalNAc-TL1 exists as two alternatively spliced isoforms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of GalNAc-TL1 isoforms 1 and 2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other GalNAc-TL family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of GalNAc-TL1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of GalNAc-TL1 of human origin |
| Entrez Gene | 57452 |
|---|
| Application Notes | recommended for detection of GalNAc-TL1 isoforms 1 and 2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other GalNAc-TL family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
