Application
Western blot analysis of PKDREJ expression in KNRK whole cell lysate (A) and mouse skeletal muscle tissue extract (B).| Product Name | PKDREJ Antibody (M-86) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 2041-2126 mapping at the C-terminus of PKDREJ of mouse origin |
| Modification Notes | PKDREJ (polycystic kidney disease and receptor for egg jelly-related protein) is a 2,253 amino acid multi-pass membrane protein that belongs to the polycystin family and is encoded by an intronless gene. Expressed exclusively in testis, PKDREJ is thought to play a key role in fertilization, possibly by generating a calcium transport channel that is directly associated with the acrosome reaction of the sperm. Human PKDREJ, which can exist as homomultimers or heteromultimers, shares 64% identity with its mouse homolog, suggesting a conserved function between species. PKDREJ contains one receptor for egg jelly (REJ) domain, eleven transmembrane domains, one G-protein-coupled receptor proteolytic site (GPS) domain and one lipoxygenase domain. Several isoforms of PKDREJ exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PKDREJ of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 2041-2126 mapping at the C-terminus of PKDREJ of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 2041-2126 mapping at the C-terminus of PKDREJ of mouse origin |
| Entrez Gene | 10343 |
|---|
Application
Western blot analysis of PKDREJ expression in KNRK whole cell lysate (A) and mouse skeletal muscle tissue extract (B).| Application Notes | recommended for detection of PKDREJ of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
