Application
Western blot analysis of VAP-A expression in non-transfected: (A) and mouse VAP-A transfected: (B) 293T whole cell lysates.| Product Name | VAP-A Antibody (H-40) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 132-170 mapping within an internal region of VAP-A of human origin |
| Modification Notes | SNAREs are compartmentally specific, integral membrane proteins that are involved in the fusion of membranes and the transport of intracellular proteins. SNAREs are expressed at high levels in all cell types. VAMP-associated protein A (VAP-A) is a SNARE regulator with high levels of expression in the intestine during late embryogenesis and early neonatal development. VAP-A binds to a wide range of SNAREs and fusion-related proteins, including Syntaxin 1A, rBet1, rSec22, åSNAP and NSF. This suggests that VAP-A may play a more general role in SNARE-mediated vesicle traffic between the ER and Golgi in nonpolarized cells. VAP-A also mediates traffic in cell membranes and may play an important role in modulating intestinal smooth muscle cell differentiation. VAP-A and p48 interact to form a stable complex in mammalian cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of VAP-A of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 132-170 mapping within an internal region of VAP-A of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 132-170 mapping within an internal region of VAP-A of human origin |
| Entrez Gene | 9218 |
|---|
Application
Western blot analysis of VAP-A expression in non-transfected: (A) and mouse VAP-A transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of VAP-A of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
