| Product Name | POU3F4 Antibody (H-62) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 75-136 mapping within an internal region of POU3F4 of human origin |
| Modification Notes | The Brn family of transcription factors are found in a highly restricted subset of neurons and are critical to the early embryonic development of the central nervous system. POU3F4 (POU domain, class 3, transcription factor 4), also known as OTF9, DFN3, DFNX2, BRAIN-4 or Brn-4, is a 361 amino acid class III POU domain protein that belongs to the Brn family. Localized to the nucleus, POU3F4 contains one POU-specific domain and one homeobox DNA-binding domain through which it is thought to function as a brain-specific transcription factor that effects neuronal development. Defects in the gene encoding POU3F4 are associated with X-linked deafness type 3 (DFN3), a disorder characterized by both progressive sensorineural deafness and conductive hearing loss caused by stapes gushers (large vestibular aqueducts). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of POU3F4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 75-136 mapping within an internal region of POU3F4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 75-136 mapping within an internal region of POU3F4 of human origin |
| Entrez Gene | 5456 |
|---|
| Application Notes | recommended for detection of POU3F4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
