| Product Name | AGXT2L1 Antibody (T-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of AGXT2L1 of human origin |
| Modification Notes | Members of the class-III pyridoxal-phosphate-dependent aminotransferase family, such as AGXT2, catalyze the conversion of glyoxylate to glycine using L-alanine as the amino donor. AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L1 (alanine-glyoxylate aminotransferase 2-like 1) is a 499 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L1 localizes to the mitochondria and exists as two alternatively spliced isoforms. Encoded by a gene located on human chromosome 4q25, AGXT2L1 may have similar functions as AGXT2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of AGXT2L1 of human origin by WB, IF and ELISA non cross-reactive with AGXT2L2: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of AGXT2L1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of AGXT2L1 of human origin |
| Entrez Gene | 64850 |
|---|
| Application Notes | recommended for detection of AGXT2L1 of human origin by WB, IF and ELISA non cross-reactive with AGXT2L2: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
