Western blot analysis of Ribosomal Protein L7A expression in non-transfected 293: (A), human Ribosomal Protein L7A transfected 293: (B) and K-562 (C) whole cell lysates.
epitope corresponding to amino acids 40-236 mapping within an internal region of Ribosomal Protein L7A of human origin
Modification Notes
Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein L7A, also known as RPL7A or SURF-3, is a 266 amino acid protein that interacts with select nuclear hormone receptors, such as TR (thyroid hormone receptor), and, via this interaction, is able to inhibit receptor function. The gene encoding Ribosomal Protein L7A maps to chromosome 9 and is subject to a recombination event which activates the Trk (tyrosine kinase receptor) oncogene and may play a role in oncogenesis. Like most ribosomal proteins, Ribosomal Protein L7A exists as multiple processed pseudogenes that are scattered throughout the genome.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Ribosomal Protein L7A of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 40-236 mapping within an internal region of Ribosomal Protein L7A of human origin
Tissue Specificity
epitope corresponding to amino acids 40-236 mapping within an internal region of Ribosomal Protein L7A of human origin
Western blot analysis of Ribosomal Protein L7A expression in non-transfected 293: (A), human Ribosomal Protein L7A transfected 293: (B) and K-562 (C) whole cell lysates.
Application Notes
recommended for detection of Ribosomal Protein L7A of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.